Afatinib BIBW 2992 Treatment for Non-small Cell Lung Cancer
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CAS No.: 9081-18-2
Chemical Name: Afatinib (BIBW 2992)
Synonyms: Tovok;ToMtovok;BIBW 2992;Afatinib Base;Afatinib, >=99%;Tovok, BIBW 2992;BIBW2992 Afatinib;Afatinib, Free Base;Afatinib (BIBW 2992);Tofacitinib and its interMediate
Formula Weight: 485.944
Afatinib is a type of biological therapy called a tyrosine kinase inhibitor (TKI). It is a treatment for non small cell lung cancer that has spread outside the lung or to other parts of the body.
How afatinib works
This type of drug works by blocking particular proteins on cancer cells that encourage the cancer to grow. Afatinib blocks proteins called epidermal growth factor receptors (EGFR). Cancers that have these receptors are called EGFR positive.
Between 10 and 15 people out of every 100 with non small cell lung cancer (10 to 15%) have EGFR positive cancer. Doctors check your cancer cells to see if they have the receptors before you have this treatment.Afatinib may shrink the cancer or stop it growing for a time.
What Afatinib Is Used For:
Afatinib is used to treat metastatic non-small cell lung cancer (NSCLC) that has certain EGFR mutations (exon 19 deletion/exon 21 substitution) as detected by an FDA-approved test.
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